The plasmid purification market facilitates manipulation of DNA for various molecular biology applications such as cloning, gene expression, validation of nucleic acid interactions and others. Plasmids are used as primitive biological tools for gene expression and cloning experiments across biotech and pharmaceutical companies.
The plasmid purification market is estimated to be valued at USD 1.98 Billion in 2024 and is expected to reach USD 4.21 Billion by 2031, exhibiting a compound annual growth rate (CAGR) of 11.4% from 2024 to 2031.
Plasmids are utilized across various academic and commercial applications such as protein production, DNA vaccine development, gene therapy development, discovery & development of recombinant therapeutics. Large scale production of plasmids for clinical research requires robust, reliable and scalable purification techniques. Key players operating in the plasmid purification market are Merck KGaA, QIAGEN, Thermo Fisher Scientific, Inc., Takara Bio, Promega Corporation, Zymo Research, MP BIOMEDICALS, New England Biolabs, MCLAB, Agilent Technologies Inc., Illumina Inc., and Applied Biological Materials Inc.
Key Takeaways
Key players: Merck KGaA, QIAGEN and Thermo Fisher Scientific Inc. dominate the plasmid purification market. Merck KGaA offers plasmid purification kits such as PureYieldTM plasmid Midiprep system, PureLink® HiPure Plasmid Filter Purification Kits and QuickLyseTM Miniprep Kit.
Growing demand: Rising Plasmid Purification Market Demand from pharmaceutical and biotech companies for gene therapy, DNA vaccines and recombinant protein production is expected to drive the plasmid purification market over the forecast period.
Technological advancements: Market players are focusing on development of automated, high throughput and scalable plasmid purification technologies to meet the needs of plasmid production at commercial and clinical scale.
Market Trends
Consolidation: Leading players are consolidating their position in the market through acquisitions of emerging companies offering novel plasmid purification technologies.
Outsourcing of plasmid production: Rising outsourcing of plasmid production to Contract Development and Manufacturing Organizations (CDMOs) is a key trend observed in the market.
Market Opportunities
Plasmid based therapies: Growing pipeline of gene and cell therapies, DNA vaccines provides lucrative opportunity for plasmid manufacturers and purification solution providers.
Development of emerging markets: Significant unmet need for advanced research infrastructure in developing countries present opportunities for market players.
Impact of COVID-19 on Plasmid Purification Market Growth
The outbreak of COVID-19 has significantly impacted the growth of plasmid purification market. During the initial outbreak, countries imposed strict lockdown and social distancing measures to curb the spread of the virus. This resulted in temporary closure of research laboratories and disrupted the supply chain globally. This adversely affected the research activities related to vaccine and drug development which utilize plasmids. Furthermore, restrictions on travel and transportation led to shortage of raw materials and disrupted manufacturing activities. However, with increasing research on COVID-19 treatment and vaccines, the demand for plasmids increased significantly in 2020. Numerous biopharmaceutical and academic research institutes intensified their efforts to develop antiviral drugs and vaccines. This boosted the sales of plasmid purification kits, enzymes and other related reagents. In post COVID times, companies have strengthened their supply chain network to ensure sustainable supply. In addition, the pandemic has increased research funding for infectious diseases which is projected to support market growth going ahead. However, sales may fluctuate with resurgence of new variants until the virus is controlled globally.
North America Plasmid Purification Market
North America dominated the global plasmid purification market in terms of value in the historical period. This was majorly driven by presence of leading pharmaceutical and biotechnology companies engaged in drug discovery and development activities in the region. The US held largest share in the regional market due presence of developed research infrastructure and increasing government funding for life science research. Additionally, rising demand for gene therapy and cell-based research in the region positively impacted the market growth. Growth prospects are high in the United States due to favorable government initiatives to support research for developing effective vaccines and treatments.
Asia Pacific Plasmid Purification Market
The Asia Pacific plasmid purification market is projected to witness fastest growth during forecast period owing to increasing Research & Development expenditures by pharmaceutical companies in emerging countries. Countries like China and India are attracting research investments due to availability of low-cost and high skilled workforce. In addition, rising prevalence of infectious diseases and cancer is driving research activities. This in turn has fueled the adoption of plasmid purification products in the region. China held prominent share in the regional market supported by strong government focus on development of biologics and biomanufacturing industries. Overall, market growth in Asia Pacific is driven by increasing collaborations between global players and local research institutes.
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About Author:
Alice Mutum is a seasoned senior content editor at Coherent Market Insights, leveraging extensive expertise gained from her previous role as a content writer. With seven years in content development, Alice masterfully employs SEO best practices and cutting-edge digital marketing strategies to craft high-ranking, impactful content. As an editor, she meticulously ensures flawless grammar and punctuation, precise data accuracy, and perfect alignment with audience needs in every research report. Alice's dedication to excellence and her strategic approach to content make her an invaluable asset in the world of market insights.
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